HCSGD entry for RPS18
1. General information
| Official gene symbol | RPS18 |
|---|---|
| Entrez ID | 6222 |
| Gene full name | ribosomal protein S18 |
| Other gene symbols | D6S218E HKE3 KE-3 KE3 S18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003735 | Structural constituent of ribosome | IBA IEA | molecular_function |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005829 | Cytosol | IBA TAS | cellular_component |
| GO:0005840 | Ribosome | IEA NAS | cellular_component |
| GO:0006412 | Translation | IBA IC IEA TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0015935 | Small ribosomal subunit | IBA IDA | cellular_component |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0019083 | Viral transcription | TAS | biological_process |
| GO:0019843 | RRNA binding | IEA | molecular_function |
| GO:0022627 | Cytosolic small ribosomal subunit | IDA | cellular_component |
| GO:0042254 | Ribosome biogenesis | IBA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8518331674 | 0.4921755594 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0273271975 |
| GSE13712_SHEAR | Down | -0.2120536177 |
| GSE13712_STATIC | Down | -0.1363999104 |
| GSE19018 | Up | 0.0912658777 |
| GSE19899_A1 | Down | -0.1177626056 |
| GSE19899_A2 | Down | -0.0674353266 |
| PubMed_21979375_A1 | Up | 0.4001813091 |
| PubMed_21979375_A2 | Down | -0.0001933147 |
| GSE35957 | Down | -0.2774557995 |
| GSE36640 | Down | -0.1724055669 |
| GSE54402 | Up | 0.2377181478 |
| GSE9593 | Up | 0.0493224051 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1634241323 |
| GSE28863_A2 | Up | 0.3712181224 |
| GSE28863_A3 | Down | -0.2791840465 |
| GSE28863_A4 | Down | -0.0023933784 |
| GSE48662 | Down | -0.2110568507 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039415 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041265 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041672 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050014 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
