HCSGD entry for RPLP2
1. General information
| Official gene symbol | RPLP2 |
|---|---|
| Entrez ID | 6181 |
| Gene full name | ribosomal protein, large, P2 |
| Other gene symbols | D11S2243E LP2 P2 RPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003735 | Structural constituent of ribosome | IEA NAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0006412 | Translation | NAS TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006414 | Translational elongation | IEA TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0019083 | Viral transcription | TAS | biological_process |
| GO:0022625 | Cytosolic large ribosomal subunit | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8576590669 | 0.4930225447 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0663544825 |
| GSE13712_SHEAR | Down | -0.4675012408 |
| GSE13712_STATIC | Up | 0.0595464999 |
| GSE19018 | Down | -0.0253016400 |
| GSE19899_A1 | Up | 0.0181641064 |
| GSE19899_A2 | Up | 0.5189923271 |
| PubMed_21979375_A1 | Up | 0.4417930089 |
| PubMed_21979375_A2 | Down | -0.1999527103 |
| GSE35957 | Up | 0.0712905430 |
| GSE36640 | Down | -0.2157080622 |
| GSE54402 | Up | 0.1703318815 |
| GSE9593 | Down | -0.3899996193 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2408654837 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-505-5p | MIMAT0004776 | MIRT037947 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039035 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041698 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051678 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
