HCSGD entry for RPL22


1. General information

Official gene symbolRPL22
Entrez ID6146
Gene full nameribosomal protein L22
Other gene symbolsEAP HBP15 HBP15/L22 L22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0003735Structural constituent of ribosomeIEA NASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006412TranslationIEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022625Cytosolic large ribosomal subunitIDAcellular_component
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0046632Alpha-beta T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97670695260.08018976100.99999024730.5355683075

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0075185682
GSE13712_SHEARDown-0.4467426174
GSE13712_STATICDown-0.3256905473
GSE19018Down-0.0481921292
GSE19899_A1Down-0.3355574285
GSE19899_A2Down-0.2626761910
PubMed_21979375_A1Down-0.2931161681
PubMed_21979375_A2Down-0.2188951654
GSE35957Up0.0208554120
GSE36640Down-0.0751003720
GSE54402Up0.1104554263
GSE9593Up0.1178253197
GSE43922Up0.0509776948
GSE24585Down-0.6599987204
GSE37065Down-0.2888745971
GSE28863_A1Down-0.0803770813
GSE28863_A2Up0.0739261287
GSE28863_A3Up0.1469074196
GSE28863_A4Down-0.0500996178
GSE48662Down-0.1679002873

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT037108CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041525CLASHFunctional MTI (Weak)23622248
hsa-miR-23b-3pMIMAT0000418MIRT046351CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048146CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049788CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.