HCSGD entry for RPL21


1. General information

Official gene symbolRPL21
Entrez ID6144
Gene full nameribosomal protein L21
Other gene symbolsL21
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0003723RNA bindingTASmolecular_function
GO:0003735Structural constituent of ribosomeIEA NASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006412TranslationIEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022625Cytosolic large ribosomal subunitIDAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94320689560.63881156110.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0807355736
GSE28863_A2Up0.0729139628
GSE28863_A3Down-0.2955280516
GSE28863_A4Up0.1091726262
GSE48662Down-0.1840915774

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031954ProteomicsFunctional MTI (Weak)18668040
hsa-miR-652-3pMIMAT0003322MIRT039492CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040024CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042180CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-5pMIMAT0000680MIRT044294CLASHFunctional MTI (Weak)23622248
hsa-miR-128-3pMIMAT0000424MIRT045855CLASHFunctional MTI (Weak)23622248
hsa-miR-221-3pMIMAT0000278MIRT046903CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048563CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050593CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050909CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.