HCSGD entry for RPA2

1. General information

Official gene symbolRPA2
Entrez ID6118
Gene full namereplication protein A2, 32kDa
Other gene symbolsREPA2 RPA32
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000718Nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0000724Double-strand break repair via homologous recombinationTASbiological_process
GO:0000730DNA recombinase assemblyTASbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003697Single-stranded DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005662DNA replication factor A complexIDA IEA IPIcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006260DNA replicationIDA TASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingTASbiological_process
GO:0006302Double-strand break repairTASbiological_process
GO:0010569Regulation of double-strand break repair via homologous recombinationIMPbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0019903Protein phosphatase bindingIPImolecular_function
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
GO:0047485Protein N-terminus bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10461625320.57898246650.67172609121.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.1207559590
GSE13712_SHEARUp0.0912875863
GSE13712_STATICUp0.0549472301
GSE19018Down-0.2281941177
GSE19899_A1Up0.5344296641
GSE19899_A2Down-0.0954653160
PubMed_21979375_A1Up0.1170519779
PubMed_21979375_A2Down-0.4673210033
GSE35957Down-0.4544542823
GSE36640Down-0.4595099340
GSE54402Up0.3732293161
GSE9593Down-0.1654384655
GSE43922Up0.6554372434
GSE24585Up0.2342995969
GSE37065Up0.0036875235
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0891434600

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020141SequencingFunctional MTI (Weak)20371350
hsa-miR-93-5pMIMAT0000093MIRT027975SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031089SequencingFunctional MTI (Weak)20371350
hsa-miR-1226-3pMIMAT0005577MIRT036453CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049074CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050504CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.