HCSGD entry for RORC
1. General information
| Official gene symbol | RORC |
|---|---|
| Entrez ID | 6097 |
| Gene full name | RAR-related orphan receptor C |
| Other gene symbols | NR1F3 RORG RZR-GAMMA RZRG TOR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003707 | Steroid hormone receptor activity | IEA | molecular_function |
| GO:0004879 | Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030522 | Intracellular receptor signaling pathway | TAS | biological_process |
| GO:0033077 | T cell differentiation in thymus | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048535 | Lymph node development | IEA | biological_process |
| GO:0048537 | Mucosal-associated lymphoid tissue development | IEA | biological_process |
| GO:0072539 | T-helper 17 cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7786327191 | 0.8165604612 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0023473326 |
| GSE13712_SHEAR | Down | -0.0944917888 |
| GSE13712_STATIC | Down | -0.0302987319 |
| GSE19018 | Up | 0.1451588415 |
| GSE19899_A1 | Up | 0.0058793267 |
| GSE19899_A2 | Up | 0.0939679992 |
| PubMed_21979375_A1 | Down | -0.0881475767 |
| PubMed_21979375_A2 | Down | -0.0801909927 |
| GSE35957 | Up | 0.1429509112 |
| GSE36640 | Up | 0.0675502607 |
| GSE54402 | Down | -0.0724962510 |
| GSE9593 | Up | 0.0972198715 |
| GSE43922 | Up | 0.0368775448 |
| GSE24585 | Down | -0.0502895118 |
| GSE37065 | Up | 0.0534933160 |
| GSE28863_A1 | Down | -0.1062349698 |
| GSE28863_A2 | Up | 0.0357789437 |
| GSE28863_A3 | Up | 0.2648281317 |
| GSE28863_A4 | Up | 0.0145656231 |
| GSE48662 | Down | -0.0865688417 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-3p | MIMAT0004589 | MIRT007283 | Luciferase reporter assay | Functional MTI | 23359619 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018972 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019468 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030126 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
