HCSGD entry for RORB
1. General information
| Official gene symbol | RORB |
|---|---|
| Entrez ID | 6096 |
| Gene full name | RAR-related orphan receptor B |
| Other gene symbols | NR1F2 ROR-BETA RZR-BETA RZRB bA133M9.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | ISS | molecular_function |
| GO:0003707 | Steroid hormone receptor activity | IEA | molecular_function |
| GO:0004879 | Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030522 | Intracellular receptor signaling pathway | TAS | biological_process |
| GO:0042462 | Eye photoreceptor cell development | ISS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | ISS | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7564610463 | 0.6138929942 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0012440101 |
| GSE13712_SHEAR | Up | 0.0223693199 |
| GSE13712_STATIC | Down | -0.0023035792 |
| GSE19018 | Down | -0.0469767015 |
| GSE19899_A1 | Up | 0.1352001018 |
| GSE19899_A2 | Down | -0.0004408293 |
| PubMed_21979375_A1 | Up | 0.1017763395 |
| PubMed_21979375_A2 | Down | -0.1115107942 |
| GSE35957 | Up | 0.1194870288 |
| GSE36640 | Up | 0.0865549298 |
| GSE54402 | Up | 0.0858293969 |
| GSE9593 | Down | -0.5043200933 |
| GSE43922 | Up | 0.0779343433 |
| GSE24585 | Down | -0.2124855858 |
| GSE37065 | Up | 0.0283782581 |
| GSE28863_A1 | Down | -0.0925380661 |
| GSE28863_A2 | Down | -0.1084387116 |
| GSE28863_A3 | Up | 0.0977871401 |
| GSE28863_A4 | Up | 0.0635737546 |
| GSE48662 | Up | 0.0519774839 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018866 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030014 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
