HCSGD entry for PAPPA2
1. General information
| Official gene symbol | PAPPA2 |
|---|---|
| Entrez ID | 60676 |
| Gene full name | pappalysin 2 |
| Other gene symbols | PAPP-A2 PAPP-E PAPPE PLAC3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001558 | Regulation of cell growth | NAS | biological_process |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005622 | Intracellular | NAS | cellular_component |
| GO:0006508 | Proteolysis | IDA | biological_process |
| GO:0008237 | Metallopeptidase activity | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | NAS | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0685447741 | 0.9459059154 | 0.5620281221 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0337602997 |
| GSE13712_SHEAR | Down | -0.1571027080 |
| GSE13712_STATIC | Up | 0.0390307260 |
| GSE19018 | Up | 0.1984591796 |
| GSE19899_A1 | Up | 0.0337548462 |
| GSE19899_A2 | Up | 0.2292927460 |
| PubMed_21979375_A1 | Up | 0.2736051741 |
| PubMed_21979375_A2 | Up | 0.0231974824 |
| GSE35957 | Up | 0.2610302551 |
| GSE36640 | Up | 0.4356665780 |
| GSE54402 | Up | 0.0021686648 |
| GSE9593 | Up | 0.3464539463 |
| GSE43922 | Up | 0.3323274027 |
| GSE24585 | Up | 0.1108878400 |
| GSE37065 | Down | -0.6777479881 |
| GSE28863_A1 | Up | 0.9082232229 |
| GSE28863_A2 | Up | 0.1139967820 |
| GSE28863_A3 | Up | 0.4375831438 |
| GSE28863_A4 | Down | -0.1578119961 |
| GSE48662 | Up | 0.1586910937 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
