HCSGD entry for ELAC2
1. General information
| Official gene symbol | ELAC2 |
|---|---|
| Entrez ID | 60528 |
| Gene full name | elaC ribonuclease Z 2 |
| Other gene symbols | ELC2 HPC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004519 | Endonuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0072684 | Mitochondrial tRNA 3'-trailer cleavage, endonucleolytic | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0568004027 | 0.9344415182 | 0.5176743075 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2563200507 |
| GSE13712_SHEAR | Down | -0.0367799321 |
| GSE13712_STATIC | Up | 0.1478239877 |
| GSE19018 | Down | -0.2281256155 |
| GSE19899_A1 | Up | 0.0771544216 |
| GSE19899_A2 | Up | 0.9556206095 |
| PubMed_21979375_A1 | Up | 1.5301904573 |
| PubMed_21979375_A2 | Up | 0.4480928888 |
| GSE35957 | Down | -0.1121044848 |
| GSE36640 | Up | 0.4670622267 |
| GSE54402 | Up | 0.1799829369 |
| GSE9593 | Down | -0.1902495437 |
| GSE43922 | Up | 0.5430058852 |
| GSE24585 | Down | -0.3208679630 |
| GSE37065 | Down | -0.0350993140 |
| GSE28863_A1 | Up | 0.3747650616 |
| GSE28863_A2 | Up | 0.0307519952 |
| GSE28863_A3 | Up | 0.0008346567 |
| GSE28863_A4 | Up | 0.0511241915 |
| GSE48662 | Down | -0.0495832052 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031823 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036843 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039981 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042299 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048834 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048960 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
