HCSGD entry for SAV1
1. General information
| Official gene symbol | SAV1 |
|---|---|
| Entrez ID | 60485 |
| Gene full name | salvador homolog 1 (Drosophila) |
| Other gene symbols | SAV WW45 WWP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001942 | Hair follicle development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0030216 | Keratinocyte differentiation | IEA | biological_process |
| GO:0035329 | Hippo signaling | ISS TAS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IEA | biological_process |
| GO:0050680 | Negative regulation of epithelial cell proliferation | IEA | biological_process |
| GO:0060044 | Negative regulation of cardiac muscle cell proliferation | IEA | biological_process |
| GO:0060412 | Ventricular septum morphogenesis | IEA | biological_process |
| GO:0060487 | Lung epithelial cell differentiation | IEA | biological_process |
| GO:0060575 | Intestinal epithelial cell differentiation | IEA | biological_process |
| GO:2000036 | Regulation of stem cell maintenance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4078488811 | 0.2955720413 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3789673590 |
| GSE13712_SHEAR | Up | 0.1098395779 |
| GSE13712_STATIC | Down | -0.0214702413 |
| GSE19018 | Up | 0.0194863058 |
| GSE19899_A1 | Down | -0.0272230818 |
| GSE19899_A2 | Up | 0.1091458885 |
| PubMed_21979375_A1 | Down | -0.7544998062 |
| PubMed_21979375_A2 | Down | -0.0084349184 |
| GSE35957 | Down | -0.0510593804 |
| GSE36640 | Down | -1.0051418734 |
| GSE54402 | Down | -0.1020595167 |
| GSE9593 | Up | 0.0733054315 |
| GSE43922 | Down | -0.1436991062 |
| GSE24585 | Up | 0.3103022287 |
| GSE37065 | Up | 0.1935474240 |
| GSE28863_A1 | Up | 0.0321591113 |
| GSE28863_A2 | Down | -0.0219141968 |
| GSE28863_A3 | Down | -0.4674680199 |
| GSE28863_A4 | Up | 0.2001302002 |
| GSE48662 | Up | 0.2601061658 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027094 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031649 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT041707 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
