HCSGD entry for SLC5A7


1. General information

Official gene symbolSLC5A7
Entrez ID60482
Gene full namesolute carrier family 5 (choline transporter), member 7
Other gene symbolsCHT CHT1 HMN7A hCHT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005307Choline:sodium symporter activityIMPmolecular_function
GO:0005886Plasma membraneIDA IEA TAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007271Synaptic transmission, cholinergicIEAbiological_process
GO:0007274Neuromuscular synaptic transmissionIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008292Acetylcholine biosynthetic processIEA IMPbiological_process
GO:0015220Choline transmembrane transporter activityIEA IMPmolecular_function
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0033265Choline bindingIEAmolecular_function
GO:0034220Ion transmembrane transportIMPbiological_process
GO:0035725Sodium ion transmembrane transportIMPbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88311313780.63871716880.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0858957148
GSE13712_SHEARDown-0.0291251939
GSE13712_STATICDown-0.0392244332
GSE19018Down-0.0518638275
GSE19899_A1Up0.1282059955
GSE19899_A2Up0.0297577505
PubMed_21979375_A1Up0.1619897811
PubMed_21979375_A2Down-0.1031180488
GSE35957Up0.1699710294
GSE36640Up0.1051944344
GSE54402Up0.0223550598
GSE9593Down-0.0656399534
GSE43922Up0.0147817950
GSE24585Down-0.1865774260
GSE37065Down-0.0685693818
GSE28863_A1Down-0.0652057475
GSE28863_A2Down-0.0527652787
GSE28863_A3Up0.1633651573
GSE28863_A4Up0.0585497558
GSE48662Down-0.1340410362

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.