HCSGD entry for ELOVL5
1. General information
| Official gene symbol | ELOVL5 |
|---|---|
| Entrez ID | 60481 |
| Gene full name | ELOVL fatty acid elongase 5 |
| Other gene symbols | HELO1 dJ483K16.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006636 | Unsaturated fatty acid biosynthetic process | IEA | biological_process |
| GO:0009922 | Fatty acid elongase activity | IDA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0033559 | Unsaturated fatty acid metabolic process | TAS | biological_process |
| GO:0034625 | Fatty acid elongation, monounsaturated fatty acid | IDA | biological_process |
| GO:0034626 | Fatty acid elongation, polyunsaturated fatty acid | IDA | biological_process |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0036109 | Alpha-linolenic acid metabolic process | TAS | biological_process |
| GO:0042761 | Very long-chain fatty acid biosynthetic process | IDA | biological_process |
| GO:0043651 | Linoleic acid metabolic process | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9812527905 | 0.1626702405 | 0.9999902473 | 0.7789697289 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0570810065 |
| GSE13712_SHEAR | Down | -0.1911101435 |
| GSE13712_STATIC | Down | -0.1472450440 |
| GSE19018 | Down | -0.4900812008 |
| GSE19899_A1 | Down | -0.0802865785 |
| GSE19899_A2 | Down | -0.0178381804 |
| PubMed_21979375_A1 | Down | -0.3217801662 |
| PubMed_21979375_A2 | Down | -0.1276324893 |
| GSE35957 | Up | 0.1193253169 |
| GSE36640 | Down | -0.0979183499 |
| GSE54402 | Up | 0.0243911053 |
| GSE9593 | Down | -0.0711051079 |
| GSE43922 | Up | 0.0067570682 |
| GSE24585 | Down | -0.1002449991 |
| GSE37065 | Down | -0.0451830115 |
| GSE28863_A1 | Down | -0.0260357931 |
| GSE28863_A2 | Up | 0.2116096287 |
| GSE28863_A3 | Down | -0.2998647069 |
| GSE28863_A4 | Down | -0.0692689743 |
| GSE48662 | Down | -0.2791802536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT001832 | Microarray//qRT-PCR//qRT-PCR;Other | Functional MTI (Weak) | 16549876 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024815 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026394 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028547 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031621 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043118 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT050635 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
