HCSGD entry for TGIF2
1. General information
| Official gene symbol | TGIF2 |
|---|---|
| Entrez ID | 60436 |
| Gene full name | TGFB-induced factor homeobox 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP TAS | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA NAS | molecular_function |
| GO:0005634 | Nucleus | IEA TAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9976425972 | 0.0143523916 | 0.9999902473 | 0.2356724267 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3617089569 |
| GSE13712_SHEAR | Down | -0.3559995837 |
| GSE13712_STATIC | Down | -0.0054644483 |
| GSE19018 | Down | -0.5503506555 |
| GSE19899_A1 | Down | -0.0665338647 |
| GSE19899_A2 | Down | -0.2420341124 |
| PubMed_21979375_A1 | Down | -0.1527528743 |
| PubMed_21979375_A2 | Down | -0.3087187227 |
| GSE35957 | Down | -0.1336554569 |
| GSE36640 | Down | -0.7500748657 |
| GSE54402 | Down | -0.1337023853 |
| GSE9593 | Down | -0.4875260796 |
| GSE43922 | Down | -0.0019305288 |
| GSE24585 | Down | -0.3753731692 |
| GSE37065 | Down | -0.2870655613 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0799782619 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148a-3p | MIMAT0000243 | MIRT000298 | Luciferase reporter assay//Western blot | Functional MTI | 18768788 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT007108 | qRT-PCR//Western blot | Functional MTI | 23469762 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025109 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027288 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-149-3p | MIMAT0004609 | MIRT038620 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052726 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
