HCSGD entry for EXOC4
1. General information
| Official gene symbol | EXOC4 |
|---|---|
| Entrez ID | 60412 |
| Gene full name | exocyst complex component 4 |
| Other gene symbols | SEC8 SEC8L1 Sec8p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000145 | Exocyst | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006904 | Vesicle docking involved in exocytosis | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0032584 | Growth cone membrane | IEA | cellular_component |
| GO:0035748 | Myelin sheath abaxonal region | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2715102048 | 0.5452444284 | 0.9684931852 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0849895709 |
| GSE13712_SHEAR | Down | -0.2701377822 |
| GSE13712_STATIC | Down | -0.0171849407 |
| GSE19018 | Up | 0.2374694679 |
| GSE19899_A1 | Down | -0.0414222317 |
| GSE19899_A2 | Down | -0.1829481356 |
| PubMed_21979375_A1 | Down | -0.1322490962 |
| PubMed_21979375_A2 | Up | 0.0310502235 |
| GSE35957 | Up | 0.3053548950 |
| GSE36640 | Down | -0.3540052799 |
| GSE54402 | Down | -0.3110107272 |
| GSE9593 | Up | 0.5832004218 |
| GSE43922 | Down | -0.2017800840 |
| GSE24585 | Up | 0.3622207968 |
| GSE37065 | Down | -0.1265528712 |
| GSE28863_A1 | Up | 0.5124718083 |
| GSE28863_A2 | Up | 0.4141244312 |
| GSE28863_A3 | Down | -0.1728257598 |
| GSE28863_A4 | Down | -0.1227797255 |
| GSE48662 | Up | 0.2269420572 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028232 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037134 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038770 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3200-3p | MIMAT0015085 | MIRT052819 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
