HCSGD entry for EDA2R

1. General information

Official gene symbolEDA2R
Entrez ID60401
Gene full nameectodysplasin A2 receptor
Other gene symbolsEDA-A2R EDAA2R TNFRSF27 XEDAR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIDAmolecular_function
GO:0005031Tumor necrosis factor-activated receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007165Signal transductionNASbiological_process
GO:0008544Epidermis developmentNASbiological_process
GO:0009790Embryo developmentNASbiological_process
GO:0012501Programmed cell deathNASbiological_process
GO:0016021Integral component of membraneICcellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0033209Tumor necrosis factor-mediated signaling pathwayNASbiological_process
GO:0046330Positive regulation of JNK cascadeIDAbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03366961360.53941263250.42241081981.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1122992269
GSE13712_SHEARUp0.6909625291
GSE13712_STATICUp0.1469647378
GSE19018Up0.1805871672
GSE19899_A1Up0.0462696224
GSE19899_A2Up0.3251641834
PubMed_21979375_A1Up2.4736891756
PubMed_21979375_A2Down-0.2872413975
GSE35957Up0.4221488715
GSE36640Down-0.2266878786
GSE54402Down-0.2377301015
GSE9593Up0.3014642606
GSE43922Up0.6546685825
GSE24585Down-0.0122001859
GSE37065Up0.4069508224
GSE28863_A1Down-0.0041360786
GSE28863_A2Down-0.7598616032
GSE28863_A3Down-0.7405741392
GSE28863_A4Up0.3037854748
GSE48662Up0.5567232504

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT016618SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.