HCSGD entry for RNASE4
1. General information
| Official gene symbol | RNASE4 |
|---|---|
| Entrez ID | 6038 |
| Gene full name | ribonuclease, RNase A family, 4 |
| Other gene symbols | RNS4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004522 | Pancreatic ribonuclease activity | NAS | molecular_function |
| GO:0005576 | Extracellular region | IDA | cellular_component |
| GO:0006379 | MRNA cleavage | NAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | NAS | biological_process |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9735661411 | 0.0036861707 | 0.9999902473 | 0.1234398219 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7625193415 |
| GSE13712_SHEAR | Down | -1.7597428487 |
| GSE13712_STATIC | Down | -0.6486366719 |
| GSE19018 | Up | 0.1933316978 |
| GSE19899_A1 | Down | -0.2940989833 |
| GSE19899_A2 | Down | -1.6113232495 |
| PubMed_21979375_A1 | Down | -0.2396268575 |
| PubMed_21979375_A2 | Down | -1.2703433685 |
| GSE35957 | Down | -0.3441384737 |
| GSE36640 | Down | -0.0327856987 |
| GSE54402 | Down | -0.4805068238 |
| GSE9593 | Up | 0.4348077215 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.3746518663 |
| GSE28863_A2 | Down | -0.1764683218 |
| GSE28863_A3 | Down | -0.3709610692 |
| GSE28863_A4 | Down | -0.0813395178 |
| GSE48662 | Down | -0.7491057168 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2'-Deoxyuridine 3'-Monophosphate | DB03448 | EXPT03183 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017156 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024338 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026275 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
