HCSGD entry for RNASE3


1. General information

Official gene symbolRNASE3
Entrez ID6037
Gene full nameribonuclease, RNase A family, 3
Other gene symbolsECP RNS3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0004540Ribonuclease activityTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006401RNA catabolic processTASbiological_process
GO:0016892Endoribonuclease activity, producing 3'-phosphomonoestersIEAmolecular_function
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69039541430.72856067400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2103899989
GSE13712_SHEARUp0.1365627625
GSE13712_STATICDown-0.0154865818
GSE19018Up0.0090512844
GSE19899_A1Up0.1500515148
GSE19899_A2Up0.0403023702
PubMed_21979375_A1Up0.3585688173
PubMed_21979375_A2Down-0.1781338011
GSE35957Up0.2966515090
GSE36640Up0.0065445918
GSE54402Down-0.0636195664
GSE9593Down-0.0114463258
GSE43922Up0.0251739134
GSE24585Down-0.0683504949
GSE37065Down-0.0222690872
GSE28863_A1Down-0.0865374240
GSE28863_A2Down-0.0727608436
GSE28863_A3Up0.1603309884
GSE28863_A4Up0.0276121537
GSE48662Up0.0491079325

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PranlukastDB01411 -
Adenosine-2'-5'-DiphosphateDB02098 EXPT00366
Citric AcidDB04272 EXPT00922

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.