HCSGD entry for RNASE2
1. General information
| Official gene symbol | RNASE2 |
|---|---|
| Entrez ID | 6036 |
| Gene full name | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| Other gene symbols | EDN RNS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004522 | Pancreatic ribonuclease activity | IEA | molecular_function |
| GO:0004540 | Ribonuclease activity | TAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0006401 | RNA catabolic process | TAS | biological_process |
| GO:0006935 | Chemotaxis | IDA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6075518027 | 0.5375738118 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0160182704 |
| GSE13712_SHEAR | Down | -0.1151261895 |
| GSE13712_STATIC | Down | -0.4354475520 |
| GSE19018 | Up | 0.2250095754 |
| GSE19899_A1 | Up | 0.0700544423 |
| GSE19899_A2 | Up | 0.0283367754 |
| PubMed_21979375_A1 | Down | -0.1096899642 |
| PubMed_21979375_A2 | Up | 0.2763839525 |
| GSE35957 | Up | 0.1095209528 |
| GSE36640 | Down | -0.0968201365 |
| GSE54402 | Down | -0.0421501583 |
| GSE9593 | Down | -0.6961521691 |
| GSE43922 | Up | 0.0105778179 |
| GSE24585 | Down | -0.0098918914 |
| GSE37065 | Up | 0.0907709876 |
| GSE28863_A1 | Up | 0.1871328294 |
| GSE28863_A2 | Down | -0.0828550461 |
| GSE28863_A3 | Up | 0.3671481343 |
| GSE28863_A4 | Up | 0.0583576338 |
| GSE48662 | Down | -0.0223760049 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenosine-3'-5'-Diphosphate | DB01812 | EXPT00370 |
| Adenosine-2'-5'-Diphosphate | DB02098 | EXPT00366 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018080 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
