HCSGD entry for AFAP1
1. General information
| Official gene symbol | AFAP1 |
|---|---|
| Entrez ID | 60312 |
| Gene full name | actin filament associated protein 1 |
| Other gene symbols | AFAP AFAP-110 AFAP110 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9402460279 | 0.0045951256 | 0.9999902473 | 0.1371679138 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1557632408 |
| GSE13712_SHEAR | Up | 0.0181063607 |
| GSE13712_STATIC | Up | 0.0092443613 |
| GSE19018 | Up | 0.1133334848 |
| GSE19899_A1 | Down | -0.9669065249 |
| GSE19899_A2 | Down | -0.5315285561 |
| PubMed_21979375_A1 | Down | -1.5008765212 |
| PubMed_21979375_A2 | Down | -0.8316104894 |
| GSE35957 | Up | 0.3211503317 |
| GSE36640 | Down | -0.0096084287 |
| GSE54402 | Down | -1.4675951213 |
| GSE9593 | Up | 0.5171310428 |
| GSE43922 | Down | -0.6843757397 |
| GSE24585 | Down | -0.2324460100 |
| GSE37065 | Down | -0.3749973184 |
| GSE28863_A1 | Down | -0.0355853963 |
| GSE28863_A2 | Up | 0.3147508817 |
| GSE28863_A3 | Down | -0.4641197714 |
| GSE28863_A4 | Down | -0.1651887317 |
| GSE48662 | Up | 0.1273776530 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023977 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029985 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
