HCSGD entry for RGS16
1. General information
| Official gene symbol | RGS16 |
|---|---|
| Entrez ID | 6004 |
| Gene full name | regulator of G-protein signaling 16 |
| Other gene symbols | A28-RGS14 A28-RGS14P RGS-R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | TAS | biological_process |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IBA TAS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | IBA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1390525892 | 0.9682003913 | 0.7501543759 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0240763115 |
| GSE13712_SHEAR | Up | 0.0320029319 |
| GSE13712_STATIC | Up | 0.1107080798 |
| GSE19018 | Down | -0.0246991475 |
| GSE19899_A1 | Up | 0.1024665693 |
| GSE19899_A2 | Up | 0.2372500308 |
| PubMed_21979375_A1 | Up | 0.3131438646 |
| PubMed_21979375_A2 | Up | 0.0224103992 |
| GSE35957 | Up | 0.0001349220 |
| GSE36640 | Up | 0.1358400670 |
| GSE54402 | Up | 0.1415452862 |
| GSE9593 | Up | 0.1118081493 |
| GSE43922 | Up | 0.2452750586 |
| GSE24585 | Up | 0.5376362093 |
| GSE37065 | Up | 0.4192186076 |
| GSE28863_A1 | Down | -0.1440984564 |
| GSE28863_A2 | Up | 0.2225777687 |
| GSE28863_A3 | Up | 0.1422068755 |
| GSE28863_A4 | Down | -0.0119048730 |
| GSE48662 | Up | 0.2007961540 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017280 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027511 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048122 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
