HCSGD entry for RGS3
1. General information
| Official gene symbol | RGS3 |
|---|---|
| Entrez ID | 5998 |
| Gene full name | regulator of G-protein signaling 3 |
| Other gene symbols | C2PA RGP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000188 | Inactivation of MAPK activity | TAS | biological_process |
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | TAS | biological_process |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IBA TAS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0651974431 | 0.9383400821 | 0.5503726427 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3796307663 |
| GSE13712_SHEAR | Down | -0.1403676792 |
| GSE13712_STATIC | Down | -0.5772580794 |
| GSE19018 | Down | -0.0041250654 |
| GSE19899_A1 | Up | 0.4154699532 |
| GSE19899_A2 | Up | 0.3799057754 |
| PubMed_21979375_A1 | Up | 0.6448884240 |
| PubMed_21979375_A2 | Up | 0.1426360851 |
| GSE35957 | Up | 0.3001223538 |
| GSE36640 | Down | -0.0247409967 |
| GSE54402 | Up | 0.3299449228 |
| GSE9593 | Up | 0.4945342069 |
| GSE43922 | Up | 0.2020522458 |
| GSE24585 | Down | -0.1479107469 |
| GSE37065 | Up | 0.0102004651 |
| GSE28863_A1 | Down | -0.2274517514 |
| GSE28863_A2 | Down | -0.1269105231 |
| GSE28863_A3 | Up | 0.1544644402 |
| GSE28863_A4 | Up | 0.1357575296 |
| GSE48662 | Up | 0.1779825123 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-126-3p | MIMAT0000445 | MIRT000966 | Luciferase reporter assay | Non-Functional MTI | 18834857 |
| hsa-miR-126-3p | MIMAT0000445 | MIRT000966 | Reporter assay | Non-Functional MTI | 21249429 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021713 | Reporter assay | Non-Functional MTI | 21249429 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029621 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
