HCSGD entry for RGS1
1. General information
| Official gene symbol | RGS1 |
|---|---|
| Entrez ID | 5996 |
| Gene full name | regulator of G-protein signaling 1 |
| Other gene symbols | 1R20 BL34 IER1 IR20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005516 | Calmodulin binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IBA TAS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | IBA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8418179400 | 0.2067136051 | 0.9999902473 | 0.8813953206 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0254938551 |
| GSE13712_SHEAR | Down | -0.0826221012 |
| GSE13712_STATIC | Down | -0.0335691592 |
| GSE19018 | Down | -0.0047412065 |
| GSE19899_A1 | Up | 0.1649965441 |
| GSE19899_A2 | Down | -0.0680250100 |
| PubMed_21979375_A1 | Up | 0.0750545959 |
| PubMed_21979375_A2 | Up | 0.2761192882 |
| GSE35957 | Up | 0.0610606116 |
| GSE36640 | Down | -0.0242393421 |
| GSE54402 | Up | 0.0803555163 |
| GSE9593 | Up | 0.0951521965 |
| GSE43922 | Up | 0.0321769791 |
| GSE24585 | Up | 0.1171394123 |
| GSE37065 | Down | -0.0042219809 |
| GSE28863_A1 | Down | -0.9841970310 |
| GSE28863_A2 | Down | -0.7931709649 |
| GSE28863_A3 | Down | -0.0266333733 |
| GSE28863_A4 | Down | -0.1137355330 |
| GSE48662 | Up | 0.0238357228 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
