HCSGD entry for RFX5
1. General information
| Official gene symbol | RFX5 |
|---|---|
| Entrez ID | 5993 |
| Gene full name | regulatory factor X, 5 (influences HLA class II expression) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7646655560 | 0.1199621405 | 0.9999902473 | 0.6655825253 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1408179771 |
| GSE13712_SHEAR | Up | 0.0439377884 |
| GSE13712_STATIC | Down | -0.0988718065 |
| GSE19018 | Up | 0.3114519130 |
| GSE19899_A1 | Down | -0.0619871408 |
| GSE19899_A2 | Up | 0.1714385185 |
| PubMed_21979375_A1 | Down | -0.6919269988 |
| PubMed_21979375_A2 | Up | 0.3833134596 |
| GSE35957 | Down | -0.2686750905 |
| GSE36640 | Up | 0.6774357244 |
| GSE54402 | Down | -0.3991761162 |
| GSE9593 | Down | -0.1414258707 |
| GSE43922 | Up | 0.0460646197 |
| GSE24585 | Down | -0.2268931942 |
| GSE37065 | Up | 0.1657270147 |
| GSE28863_A1 | Down | -0.4654363039 |
| GSE28863_A2 | Up | 0.0837579317 |
| GSE28863_A3 | Down | -0.3915671091 |
| GSE28863_A4 | Down | -0.2438336010 |
| GSE48662 | Down | -0.0215275025 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026061 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032137 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042366 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
