HCSGD entry for RFX4


1. General information

Official gene symbolRFX4
Entrez ID5992
Gene full nameregulatory factor X, 4 (influences HLA class II expression)
Other gene symbolsNYD-SP10
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0021516Dorsal spinal cord developmentIEAbiological_process
GO:0021696Cerebellar cortex morphogenesisIEAbiological_process
GO:0030900Forebrain developmentIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54816105390.94741353670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0403818423
GSE13712_SHEARDown-0.0035711423
GSE13712_STATICUp0.0318645301
GSE19018Up0.0274794000
GSE19899_A1Up0.1387766360
GSE19899_A2Up0.0783158525
PubMed_21979375_A1Up0.0211946070
PubMed_21979375_A2Up0.1924022586
GSE35957Up0.0829765763
GSE36640Up0.0435502233
GSE54402Up0.0678906065
GSE9593Down-0.0801062859
GSE43922Up0.0783437713
GSE24585Up0.0982584991
GSE37065Up0.0876719357
GSE28863_A1Down-0.0360905440
GSE28863_A2Down-0.1192311758
GSE28863_A3Up0.1896449903
GSE28863_A4Up0.0925561522
GSE48662Up0.0141093042

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.