HCSGD entry for RFC5
1. General information
| Official gene symbol | RFC5 |
|---|---|
| Entrez ID | 5985 |
| Gene full name | replication factor C (activator 1) 5, 36.5kDa |
| Other gene symbols | RFC36 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000722 | Telomere maintenance via recombination | TAS | biological_process |
| GO:0000723 | Telomere maintenance | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005663 | DNA replication factor C complex | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA NAS TAS | biological_process |
| GO:0006271 | DNA strand elongation involved in DNA replication | TAS | biological_process |
| GO:0006281 | DNA repair | NAS TAS | biological_process |
| GO:0006283 | Transcription-coupled nucleotide-excision repair | TAS | biological_process |
| GO:0006289 | Nucleotide-excision repair | TAS | biological_process |
| GO:0006297 | Nucleotide-excision repair, DNA gap filling | TAS | biological_process |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0019899 | Enzyme binding | NAS | molecular_function |
| GO:0032201 | Telomere maintenance via semi-conservative replication | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9926651343 | 0.0019529539 | 0.9999902473 | 0.0846848435 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3433997076 |
| GSE13712_SHEAR | Down | -0.6084975059 |
| GSE13712_STATIC | Down | -0.0640305926 |
| GSE19018 | Down | -0.0487777328 |
| GSE19899_A1 | Down | -0.2953717774 |
| GSE19899_A2 | Down | -2.2351368399 |
| PubMed_21979375_A1 | Down | -0.5041750404 |
| PubMed_21979375_A2 | Down | -2.3328226582 |
| GSE35957 | Down | -1.0389472664 |
| GSE36640 | Down | -1.4807069213 |
| GSE54402 | Down | -0.1246119373 |
| GSE9593 | Down | -0.8594769363 |
| GSE43922 | Down | -0.7502449533 |
| GSE24585 | Up | 0.0446847954 |
| GSE37065 | Down | -0.2755260408 |
| GSE28863_A1 | Up | 0.0148141933 |
| GSE28863_A2 | Up | 0.2632373912 |
| GSE28863_A3 | Down | -0.2109086292 |
| GSE28863_A4 | Down | -0.0573358061 |
| GSE48662 | Down | -0.8457988476 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016278 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-1 | MIMAT0000416 | MIRT023584 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042743 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
