HCSGD entry for RFC3

1. General information

Official gene symbolRFC3
Entrez ID5983
Gene full namereplication factor C (activator 1) 3, 38kDa
Other gene symbolsRFC38
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0000731DNA synthesis involved in DNA repairTASbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0003689DNA clamp loader activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005663DNA replication factor C complexIDA TAScellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006260DNA replicationIDA TASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingTASbiological_process
GO:0016887ATPase activityIDAmolecular_function
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
GO:0046683Response to organophosphorusIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98074708030.00011850610.99999024730.0196176101

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6314624526
GSE13712_SHEARDown-0.2598248284
GSE13712_STATICDown-0.3003099582
GSE19018Down-0.5279997488
GSE19899_A1Down-0.7384582594
GSE19899_A2Down-2.8594379718
PubMed_21979375_A1Down-1.5861019415
PubMed_21979375_A2Down-2.9810907976
GSE35957Down-1.7482589847
GSE36640Down-2.7128714865
GSE54402Down-0.4690853156
GSE9593Down-1.0511672153
GSE43922Down-1.5126772034
GSE24585Down-0.0873537391
GSE37065Down-0.2368081637
GSE28863_A1Down-0.1317862191
GSE28863_A2Up1.0160891337
GSE28863_A3Down-0.7589070231
GSE28863_A4Up0.2444075773
GSE48662Down-1.0969655806

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022240Proteomics;MicroarrayNon-Functional MTI (Weak)18668037
hsa-miR-93-5pMIMAT0000093MIRT048816CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050570CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.