HCSGD entry for REL
1. General information
| Official gene symbol | REL |
|---|---|
| Entrez ID | 5966 |
| Gene full name | v-rel reticuloendotheliosis viral oncogene homolog (avian) |
| Other gene symbols | C-Rel |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001816 | Cytokine production | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IEA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IEP | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045084 | Positive regulation of interleukin-12 biosynthetic process | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
| GO:1901215 | Negative regulation of neuron death | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8469006877 | 0.0404255195 | 0.9999902473 | 0.3794149376 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8951735140 |
| GSE13712_SHEAR | Down | -0.1381185240 |
| GSE13712_STATIC | Down | -0.3487493554 |
| GSE19018 | Down | -0.0024854813 |
| GSE19899_A1 | Down | -0.0193622653 |
| GSE19899_A2 | Down | -0.2804842138 |
| PubMed_21979375_A1 | Up | 0.5583335150 |
| PubMed_21979375_A2 | Down | -0.1686912885 |
| GSE35957 | Down | -0.3175139467 |
| GSE36640 | Down | -0.8692323209 |
| GSE54402 | Up | 0.0263736361 |
| GSE9593 | Down | -0.0793825528 |
| GSE43922 | Down | -0.0183831356 |
| GSE24585 | Down | -0.5476766522 |
| GSE37065 | Up | 0.3520701305 |
| GSE28863_A1 | Up | 0.6291612918 |
| GSE28863_A2 | Up | 0.2994784944 |
| GSE28863_A3 | Down | -0.4660220209 |
| GSE28863_A4 | Down | -0.3166768356 |
| GSE48662 | Down | -0.2173937515 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027520 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
