HCSGD entry for LGR6
1. General information
| Official gene symbol | LGR6 |
|---|---|
| Entrez ID | 59352 |
| Gene full name | leucine-rich repeat containing G protein-coupled receptor 6 |
| Other gene symbols | GPCR VTS20631 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | ISS | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005887 | Integral component of plasma membrane | ISS | cellular_component |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0032588 | Trans-Golgi network membrane | ISS | cellular_component |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3012817902 | 0.8804329129 | 0.9996978348 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2517702977 |
| GSE13712_SHEAR | Up | 0.2691473867 |
| GSE13712_STATIC | Up | 0.3705166675 |
| GSE19018 | Up | 0.1104445657 |
| GSE19899_A1 | Up | 0.0845640112 |
| GSE19899_A2 | Down | -0.0987934623 |
| PubMed_21979375_A1 | Down | -0.0862374897 |
| PubMed_21979375_A2 | Up | 0.1065154788 |
| GSE35957 | Down | -0.0211228913 |
| GSE36640 | Up | 0.1760502642 |
| GSE54402 | Down | -0.0853073845 |
| GSE9593 | Up | 0.1712236296 |
| GSE43922 | Up | 0.0215550773 |
| GSE24585 | Up | 0.1857646030 |
| GSE37065 | Down | -0.0668469667 |
| GSE28863_A1 | Down | -0.2514702672 |
| GSE28863_A2 | Down | -0.1383098745 |
| GSE28863_A3 | Up | 0.3037310853 |
| GSE28863_A4 | Up | 0.1283557558 |
| GSE48662 | Down | -0.0576964905 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017776 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
