HCSGD entry for RBBP7
1. General information
| Official gene symbol | RBBP7 |
|---|---|
| Entrez ID | 5931 |
| Gene full name | retinoblastoma binding protein 7 |
| Other gene symbols | RbAp46 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006334 | Nucleosome assembly | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0016581 | NuRD complex | IDA | cellular_component |
| GO:0030308 | Negative regulation of cell growth | IDA | biological_process |
| GO:0034080 | CENP-A containing nucleosome assembly at centromere | TAS | biological_process |
| GO:0035098 | ESC/E(Z) complex | IDA | cellular_component |
| GO:0070370 | Cellular heat acclimation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9780609057 | 0.0098105771 | 0.9999902473 | 0.1962189970 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2027549851 |
| GSE13712_SHEAR | Up | 0.0901249139 |
| GSE13712_STATIC | Up | 0.0987116005 |
| GSE19018 | Down | -0.0736314338 |
| GSE19899_A1 | Down | -0.3662402795 |
| GSE19899_A2 | Down | -0.5467522798 |
| PubMed_21979375_A1 | Down | -0.8263842658 |
| PubMed_21979375_A2 | Down | -0.9012099716 |
| GSE35957 | Down | -0.2461467714 |
| GSE36640 | Down | -0.8343184791 |
| GSE54402 | Down | -0.3313887130 |
| GSE9593 | Down | -0.3249748452 |
| GSE43922 | Down | -0.4498913823 |
| GSE24585 | Down | -0.8244110022 |
| GSE37065 | Up | 0.0926476677 |
| GSE28863_A1 | Up | 0.3080229499 |
| GSE28863_A2 | Up | 0.1294946270 |
| GSE28863_A3 | Down | -0.4262732922 |
| GSE28863_A4 | Up | 0.2477963569 |
| GSE48662 | Down | -0.5692743851 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT016133 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028061 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30e-3p | MIMAT0000693 | MIRT044126 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046129 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049160 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
