HCSGD entry for RALB
1. General information
| Official gene symbol | RALB |
|---|---|
| Entrez ID | 5899 |
| Gene full name | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | IDA | biological_process |
| GO:0001928 | Regulation of exocyst assembly | ISS | biological_process |
| GO:0003924 | GTPase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007265 | Ras protein signal transduction | IEA TAS | biological_process |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0060178 | Regulation of exocyst localization | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0928312184 | 0.5420410395 | 0.6390117416 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3632119124 |
| GSE13712_SHEAR | Down | -0.0626489669 |
| GSE13712_STATIC | Down | -0.5862898699 |
| GSE19018 | Up | 0.2095047971 |
| GSE19899_A1 | Up | 0.5267408911 |
| GSE19899_A2 | Up | 0.4807227287 |
| PubMed_21979375_A1 | Down | -0.2135509855 |
| PubMed_21979375_A2 | Up | 0.0166542336 |
| GSE35957 | Down | -0.1609285491 |
| GSE36640 | Up | 0.0567771785 |
| GSE54402 | Up | 0.8399466647 |
| GSE9593 | Up | 0.4707783277 |
| GSE43922 | Up | 0.3251704753 |
| GSE24585 | Up | 0.0751456821 |
| GSE37065 | Up | 0.0835946219 |
| GSE28863_A1 | Down | -0.2169843703 |
| GSE28863_A2 | Up | 0.2141966326 |
| GSE28863_A3 | Down | -0.6523462632 |
| GSE28863_A4 | Down | -0.1034760485 |
| GSE48662 | Down | -0.4976272150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023622 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025261 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052235 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
