HCSGD entry for RAC3

1. General information

Official gene symbolRAC3
Entrez ID5881
Gene full nameras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006184GTP catabolic processIDAbiological_process
GO:0007264Small GTPase mediated signal transductionIEA TASbiological_process
GO:0008152Metabolic processIDAbiological_process
GO:0012505Endomembrane systemIDAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0030031Cell projection assemblyIDAbiological_process
GO:0030036Actin cytoskeleton organizationIDAbiological_process
GO:0030426Growth coneIDAcellular_component
GO:0031175Neuron projection developmentIEAbiological_process
GO:0031941Filamentous actinIDAcellular_component
GO:0033630Positive regulation of cell adhesion mediated by integrinIDAbiological_process
GO:0035556Intracellular signal transductionTASbiological_process
GO:0043005Neuron projectionIDAcellular_component
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0048306Calcium-dependent protein bindingIPImolecular_function
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0071944Cell peripheryIDAcellular_component
GO:1900026Positive regulation of substrate adhesion-dependent cell spreadingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76880486680.07608363660.99999024730.5206961518

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0902509941
GSE13712_SHEARDown-0.0904881998
GSE13712_STATICUp0.4990801797
GSE19018Up0.0961761992
GSE19899_A1Down-0.3720758210
GSE19899_A2Up0.0656415773
PubMed_21979375_A1Down-0.0421768450
PubMed_21979375_A2Down-1.5367588222
GSE35957Down-0.1780480207
GSE36640Up0.1252935688
GSE54402Up0.0458213504
GSE9593Up0.2200804419
GSE43922Down-0.3818166989
GSE24585Down-0.2669280778
GSE37065Down-0.2037413219
GSE28863_A1Down-0.3019671688
GSE28863_A2Up0.1276421151
GSE28863_A3Up0.3634341981
GSE28863_A4Down-0.0835230770
GSE48662Up0.1305478405

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30c-2-3pMIMAT0004550MIRT038692CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.