HCSGD entry for RABGGTA
1. General information
| Official gene symbol | RABGGTA |
|---|---|
| Entrez ID | 5875 |
| Gene full name | Rab geranylgeranyltransferase, alpha subunit |
| Other gene symbols | PTAR3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004663 | Rab geranylgeranyltransferase activity | IEA ISS | molecular_function |
| GO:0005968 | Rab-protein geranylgeranyltransferase complex | ISS | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008318 | Protein prenyltransferase activity | IEA | molecular_function |
| GO:0017137 | Rab GTPase binding | ISS | molecular_function |
| GO:0018342 | Protein prenylation | IEA | biological_process |
| GO:0018344 | Protein geranylgeranylation | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0135539417 | 0.9635262338 | 0.2903194467 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2540329817 |
| GSE13712_SHEAR | Up | 0.3806071524 |
| GSE13712_STATIC | Up | 0.4229565991 |
| GSE19018 | Up | 0.1469769451 |
| GSE19899_A1 | Up | 0.1261664991 |
| GSE19899_A2 | Up | 0.7946957748 |
| PubMed_21979375_A1 | Up | 1.6871029291 |
| PubMed_21979375_A2 | Up | 2.1694172721 |
| GSE35957 | Up | 0.2117163767 |
| GSE36640 | Up | 0.3433505981 |
| GSE54402 | Up | 0.2570038327 |
| GSE9593 | Down | -0.1284966438 |
| GSE43922 | Up | 0.3596614415 |
| GSE24585 | Down | -0.1049580531 |
| GSE37065 | Up | 0.2034240656 |
| GSE28863_A1 | Up | 0.0312119363 |
| GSE28863_A2 | Down | -0.2217945782 |
| GSE28863_A3 | Down | -0.3647637239 |
| GSE28863_A4 | Down | -0.1058629389 |
| GSE48662 | Up | 0.4046189966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-Formylmethionine | DB04464 | EXPT01455 |
| FARNESYL DIPHOSPHATE | DB07780 | - |
| GERANYLGERANYL DIPHOSPHATE | DB07841 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029542 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
