HCSGD entry for RAB6A
1. General information
| Official gene symbol | RAB6A |
|---|---|
| Entrez ID | 5870 |
| Gene full name | RAB6A, member RAS oncogene family |
| Other gene symbols | RAB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000042 | Protein targeting to Golgi | IDA | biological_process |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA IEA | molecular_function |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005802 | Trans-Golgi network | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | IDA TAS | biological_process |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0018125 | Peptidyl-cysteine methylation | IDA | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
| GO:0034067 | Protein localization to Golgi apparatus | IDA | biological_process |
| GO:0072385 | Minus-end-directed organelle transport along microtubule | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1460340375 | 0.9052227879 | 0.7661474786 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0926470829 |
| GSE13712_SHEAR | Down | -0.0716559355 |
| GSE13712_STATIC | Up | 0.0298253722 |
| GSE19018 | Up | 0.2606312082 |
| GSE19899_A1 | Up | 0.0976235147 |
| GSE19899_A2 | Up | 0.1879664330 |
| PubMed_21979375_A1 | Down | -1.0755500102 |
| PubMed_21979375_A2 | Up | 0.1886682738 |
| GSE35957 | Up | 0.0132332287 |
| GSE36640 | Down | -0.0710291134 |
| GSE54402 | Up | 0.2334842307 |
| GSE9593 | Up | 0.2049280491 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.3427739935 |
| GSE28863_A2 | Up | 0.3913618977 |
| GSE28863_A3 | Up | 0.1474091653 |
| GSE28863_A4 | Down | -0.0074560782 |
| GSE48662 | Up | 0.0205366163 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001509 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018651 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-375 | MIMAT0000728 | MIRT019966 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021193 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031010 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043017 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
