HCSGD entry for RGL2

1. General information

Official gene symbolRGL2
Entrez ID5863
Gene full nameral guanine nucleotide dissociation stimulator-like 2
Other gene symbolsHKE1.5 KE1.5 RAB2L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005088Ras guanyl-nucleotide exchange factor activityNASmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005622IntracellularIEAcellular_component
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007265Ras protein signal transductionNASbiological_process
GO:0032318Regulation of Ras GTPase activityNASbiological_process
GO:0043087Regulation of GTPase activityNASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02505529430.96164865700.37279841721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2649177334
GSE13712_SHEARDown-0.3329785546
GSE13712_STATICDown-0.4630062594
GSE19018Up0.3003210767
GSE19899_A1Up0.2372734681
GSE19899_A2Up0.6686253534
PubMed_21979375_A1Up0.9329647013
PubMed_21979375_A2Up1.7766384978
GSE35957Down-0.3292014598
GSE36640Up0.4009484685
GSE54402Up0.3254796436
GSE9593Up0.0456949424
GSE43922Up0.2739749851
GSE24585Up0.4517628201
GSE37065Down-0.0055864728
GSE28863_A1Up0.2830868086
GSE28863_A2Up0.1693579545
GSE28863_A3Up0.0533937699
GSE28863_A4Down-0.1460782353
GSE48662Up0.1158420932

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018288MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.