HCSGD entry for DNASE2B

1. General information

Official gene symbolDNASE2B
Entrez ID58511
Gene full namedeoxyribonuclease II beta
Other gene symbolsDLAD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004531Deoxyribonuclease II activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005764LysosomeIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59991484370.88580056230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0539738150
GSE13712_SHEARUp0.0980132344
GSE13712_STATICDown-0.1624677358
GSE19018Up0.0928147073
GSE19899_A1Up0.0811840154
GSE19899_A2Up0.0496774705
PubMed_21979375_A1Up0.2585182874
PubMed_21979375_A2Up0.0933879579
GSE35957Down-0.0347207894
GSE36640Up0.1567593861
GSE54402Down-0.0601617760
GSE9593Up0.2140734387
GSE43922Up0.0118004408
GSE24585Up0.1657765546
GSE37065Down-0.0960882913
GSE28863_A1Up0.0578885089
GSE28863_A2Up0.0671830190
GSE28863_A3Up0.0477993963
GSE28863_A4Up0.0240365399
GSE48662Up0.0415195419

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016923MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.