HCSGD entry for PRODH2


1. General information

Official gene symbolPRODH2
Entrez ID58510
Gene full nameproline dehydrogenase (oxidase) 2
Other gene symbolsHSPOX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004657Proline dehydrogenase activityIEAmolecular_function
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0006537Glutamate biosynthetic processIEAbiological_process
GO:0006562Proline catabolic processIEAbiological_process
GO:0010133Proline catabolic process to glutamateIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59927907750.78296195430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1002497026
GSE13712_SHEARDown-0.0737840185
GSE13712_STATICUp0.1497691782
GSE19018Up0.1812294713
GSE19899_A1Up0.0677535341
GSE19899_A2Up0.1978234749
PubMed_21979375_A1Down-0.2051836743
PubMed_21979375_A2Up0.1020978803
GSE35957Up0.2271998313
GSE36640Down-0.0591196651
GSE54402Up0.0254331833
GSE9593Down-0.0117292148
GSE43922Up0.0212561550
GSE24585Down-0.0443065706
GSE37065Down-0.0692490349
GSE28863_A1Down-0.1532855302
GSE28863_A2Down-0.1365156656
GSE28863_A3Up0.3917180129
GSE28863_A4Up0.1311588159
GSE48662Down-0.0764547237

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.