HCSGD entry for SRPRB


1. General information

Official gene symbolSRPRB
Entrez ID58477
Gene full namesignal recognition particle receptor, B subunit
Other gene symbolsAPMCF1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005525GTP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005881Cytoplasmic microtubuleIDAcellular_component
GO:0006412TranslationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02124664720.46715077690.35132846391.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7949537605
GSE13712_SHEARUp0.2919199655
GSE13712_STATICUp0.3392186139
GSE19018Down-0.8942768665
GSE19899_A1Up0.4554346855
GSE19899_A2Up0.3482930414
PubMed_21979375_A1Up1.1018523351
PubMed_21979375_A2Up0.6732630715
GSE35957Down-0.1166474280
GSE36640Up1.1915981266
GSE54402Up0.1842600653
GSE9593Up0.1201233672
GSE43922Up0.6194345421
GSE24585Down-0.5717861635
GSE37065Down-0.1800683978
GSE28863_A1Up0.0204067727
GSE28863_A2Up0.1874292996
GSE28863_A3Down-0.5453970398
GSE28863_A4Down-0.1718093500
GSE48662Down-0.0775438086

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001408pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-92a-3pMIMAT0000092MIRT049089CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.