HCSGD entry for PURB
1. General information
| Official gene symbol | PURB |
|---|---|
| Entrez ID | 5814 |
| Gene full name | purine-rich element binding protein B |
| Other gene symbols | PURBETA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003690 | Double-stranded DNA binding | IEA | molecular_function |
| GO:0003697 | Single-stranded DNA binding | ISS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003729 | MRNA binding | ISS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005662 | DNA replication factor A complex | ISS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008134 | Transcription factor binding | ISS | molecular_function |
| GO:0045637 | Regulation of myeloid cell differentiation | NAS | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046332 | SMAD binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6770416360 | 0.7388431709 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1079683552 |
| GSE13712_SHEAR | Down | -0.0719035978 |
| GSE13712_STATIC | Down | -0.0155600537 |
| GSE19018 | Up | 0.0351758737 |
| GSE19899_A1 | Up | 0.0766220457 |
| GSE19899_A2 | Down | -0.0343257126 |
| PubMed_21979375_A1 | Up | 0.2864045142 |
| PubMed_21979375_A2 | Down | -0.0988774097 |
| GSE35957 | Up | 0.0937955119 |
| GSE36640 | Down | -0.6381509721 |
| GSE54402 | Up | 0.4548177114 |
| GSE9593 | Up | 0.0776418008 |
| GSE43922 | Up | 0.0381702241 |
| GSE24585 | Down | -0.1017423670 |
| GSE37065 | Down | -0.0179197434 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1556809439 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030938 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-320b | MIMAT0005792 | MIRT036203 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-935 | MIMAT0004978 | MIRT036639 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049459 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
