HCSGD entry for RAD1
1. General information
| Official gene symbol | RAD1 |
|---|---|
| Entrez ID | 5810 |
| Gene full name | RAD1 homolog (S. pombe) |
| Other gene symbols | HRAD1 REC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000075 | Cell cycle checkpoint | NAS | biological_process |
| GO:0000077 | DNA damage checkpoint | IMP | biological_process |
| GO:0003684 | Damaged DNA binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | TAS | biological_process |
| GO:0007128 | Meiotic prophase I | TAS | biological_process |
| GO:0008408 | 3'-5' exonuclease activity | IDA | molecular_function |
| GO:0008853 | Exodeoxyribonuclease III activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0071479 | Cellular response to ionizing radiation | IDA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9943582387 | 0.0022255271 | 0.9999902473 | 0.0908187597 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2624134053 |
| GSE13712_SHEAR | Down | -0.1632805933 |
| GSE13712_STATIC | Down | -0.1590809276 |
| GSE19018 | Down | -0.3031487019 |
| GSE19899_A1 | Down | -0.8317730306 |
| GSE19899_A2 | Down | -1.2753071967 |
| PubMed_21979375_A1 | Down | -1.3797880186 |
| PubMed_21979375_A2 | Down | -1.2812326789 |
| GSE35957 | Down | -0.4496891279 |
| GSE36640 | Down | -0.7331672959 |
| GSE54402 | Down | -0.3960787380 |
| GSE9593 | Up | 0.2854492511 |
| GSE43922 | Down | -0.4898997667 |
| GSE24585 | Up | 0.4239625003 |
| GSE37065 | Down | -0.2746127194 |
| GSE28863_A1 | Down | -0.3035125604 |
| GSE28863_A2 | Up | 0.0599637166 |
| GSE28863_A3 | Down | -0.6890222934 |
| GSE28863_A4 | Down | -0.4298661182 |
| GSE48662 | Down | -0.0004996936 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020681 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024409 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026379 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-943 | MIMAT0004986 | MIRT036556 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
