HCSGD entry for PTPRG
1. General information
| Official gene symbol | PTPRG |
|---|---|
| Entrez ID | 5793 |
| Gene full name | protein tyrosine phosphatase, receptor type, G |
| Other gene symbols | HPTPG PTPG R-PTP-GAMMA RPTPG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IDA | molecular_function |
| GO:0005001 | Transmembrane receptor protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | TAS | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0010977 | Negative regulation of neuron projection development | IEA | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IDA TAS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0470360473 | 0.5670729835 | 0.4802644436 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0401291823 |
| GSE13712_SHEAR | Down | -0.3480335930 |
| GSE13712_STATIC | Down | -0.3548432836 |
| GSE19018 | Down | -0.2670251618 |
| GSE19899_A1 | Up | 0.0878751943 |
| GSE19899_A2 | Down | -0.0293448142 |
| PubMed_21979375_A1 | Up | 0.2432766318 |
| PubMed_21979375_A2 | Up | 0.4945807785 |
| GSE35957 | Up | 0.4345783262 |
| GSE36640 | Up | 0.5609534085 |
| GSE54402 | Down | -0.4343448987 |
| GSE9593 | Up | 0.2182884097 |
| GSE43922 | Up | 0.2201555382 |
| GSE24585 | Up | 0.1464698220 |
| GSE37065 | Down | -0.3072888252 |
| GSE28863_A1 | Up | 1.2098244554 |
| GSE28863_A2 | Up | 0.7317882068 |
| GSE28863_A3 | Up | 0.2988408224 |
| GSE28863_A4 | Down | -0.2453871219 |
| GSE48662 | Up | 0.1675541069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020238 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031199 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038215 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-624-5p | MIMAT0003293 | MIRT039600 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041395 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047641 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
