HCSGD entry for NKX3-2
1. General information
| Official gene symbol | NKX3-2 |
|---|---|
| Entrez ID | 579 |
| Gene full name | NK3 homeobox 2 |
| Other gene symbols | BAPX1 NKX3.2 NKX3B SMMD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007368 | Determination of left/right symmetry | IEA | biological_process |
| GO:0031016 | Pancreas development | IEA | biological_process |
| GO:0032331 | Negative regulation of chondrocyte differentiation | ISS | biological_process |
| GO:0042474 | Middle ear morphogenesis | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048536 | Spleen development | IEA | biological_process |
| GO:0048645 | Organ formation | IEA | biological_process |
| GO:0048705 | Skeletal system morphogenesis | IEA | biological_process |
| GO:0048706 | Embryonic skeletal system development | IEA | biological_process |
| GO:0060576 | Intestinal epithelial cell development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1777179476 | 0.9248313552 | 0.8267150557 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0384688247 |
| GSE13712_SHEAR | Down | -0.1584961521 |
| GSE13712_STATIC | Down | -0.2367557768 |
| GSE19018 | Down | -0.0971744749 |
| GSE19899_A1 | Up | 0.0893825628 |
| GSE19899_A2 | Up | 0.1802153003 |
| PubMed_21979375_A1 | Down | -0.0676911273 |
| PubMed_21979375_A2 | Up | 0.6046298821 |
| GSE35957 | Up | 0.3484809480 |
| GSE36640 | Up | 0.1311123144 |
| GSE54402 | Up | 0.2198451347 |
| GSE9593 | Down | -0.1443710961 |
| GSE43922 | Up | 0.1965850662 |
| GSE24585 | Up | 0.2708133234 |
| GSE37065 | Up | 0.0851971115 |
| GSE28863_A1 | Down | -0.1747500920 |
| GSE28863_A2 | Up | 0.1043691165 |
| GSE28863_A3 | Up | 0.3114528066 |
| GSE28863_A4 | Up | 0.1487786179 |
| GSE48662 | Up | 0.0116641151 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018824 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025136 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030139 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
