HCSGD entry for CWC22
1. General information
| Official gene symbol | CWC22 |
|---|---|
| Entrez ID | 57703 |
| Gene full name | CWC22 spliceosome-associated protein homolog (S. cerevisiae) |
| Other gene symbols | EIF4GL NCM fSAPb |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003723 | RNA binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0048024 | Regulation of mRNA splicing, via spliceosome | IC | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1713130998 | 0.3874031306 | 0.8136467640 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1080719823 |
| GSE13712_SHEAR | Up | 0.3142913423 |
| GSE13712_STATIC | Up | 0.2392505967 |
| GSE19018 | Down | -0.4060679359 |
| GSE19899_A1 | Up | 0.2484627713 |
| GSE19899_A2 | Up | 0.1678741837 |
| PubMed_21979375_A1 | Up | 0.3063651168 |
| PubMed_21979375_A2 | Up | 0.1573487575 |
| GSE35957 | Down | -0.5102021122 |
| GSE36640 | Down | -0.4030966899 |
| GSE54402 | Up | 0.1705154653 |
| GSE9593 | Down | -0.3046010063 |
| GSE43922 | Up | 0.1771485797 |
| GSE24585 | Down | -0.0024192058 |
| GSE37065 | Up | 0.0418207170 |
| GSE28863_A1 | Up | 0.5778672487 |
| GSE28863_A2 | Up | 0.7114034008 |
| GSE28863_A3 | Down | -0.2966355124 |
| GSE28863_A4 | Down | -0.1788686062 |
| GSE48662 | Down | -0.2946570731 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT037138 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039856 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041798 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
