HCSGD entry for FANCM
1. General information
| Official gene symbol | FANCM |
|---|---|
| Entrez ID | 57697 |
| Gene full name | Fanconi anemia, complementation group M |
| Other gene symbols | FAAP250 KIAA1596 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000712 | Resolution of meiotic recombination intermediates | IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0004518 | Nuclease activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006259 | DNA metabolic process | IEA | biological_process |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0031297 | Replication fork processing | IMP | biological_process |
| GO:0043240 | Fanconi anaemia nuclear complex | IDA | cellular_component |
| GO:0071821 | FANCM-MHF complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2709094069 | 0.2322740853 | 0.9680727260 | 0.9281471008 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0522103017 |
| GSE13712_SHEAR | Up | 0.2077896935 |
| GSE13712_STATIC | Up | 0.0562506255 |
| GSE19018 | Down | -0.0252376006 |
| GSE19899_A1 | Up | 0.0964466465 |
| GSE19899_A2 | Down | -0.6673713449 |
| PubMed_21979375_A1 | Up | 0.8593029826 |
| PubMed_21979375_A2 | Down | -0.0196216465 |
| GSE35957 | Down | -0.3546850670 |
| GSE36640 | Down | -1.0423342980 |
| GSE54402 | Up | 0.0995178957 |
| GSE9593 | Down | -0.2447882531 |
| GSE43922 | Up | 0.0978931236 |
| GSE24585 | Up | 0.4008052521 |
| GSE37065 | Down | -0.0150409083 |
| GSE28863_A1 | Up | 0.0684743869 |
| GSE28863_A2 | Up | 0.8172698224 |
| GSE28863_A3 | Down | -0.7626598740 |
| GSE28863_A4 | Up | 0.2547570191 |
| GSE48662 | Down | -0.5807550040 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016474 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026567 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
