HCSGD entry for PTN
1. General information
| Official gene symbol | PTN |
|---|---|
| Entrez ID | 5764 |
| Gene full name | pleiotrophin |
| Other gene symbols | HARP HBGF8 HBNF NEGF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004864 | Protein phosphatase inhibitor activity | TAS | molecular_function |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0007185 | Transmembrane receptor protein tyrosine phosphatase signaling pathway | TAS | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007612 | Learning | IEA | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0030282 | Bone mineralization | IEA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0051781 | Positive regulation of cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9982298773 | 0.0000100414 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.9622103063 |
| GSE13712_SHEAR | Up | 0.0145831719 |
| GSE13712_STATIC | Down | -0.0987189351 |
| GSE19018 | Down | -0.3478835443 |
| GSE19899_A1 | Down | -3.2388667136 |
| GSE19899_A2 | Down | -4.6634081164 |
| PubMed_21979375_A1 | Down | -5.5081321130 |
| PubMed_21979375_A2 | Down | -5.9321487177 |
| GSE35957 | Down | -2.9937061927 |
| GSE36640 | Down | -1.8838402848 |
| GSE54402 | Down | -2.5438730233 |
| GSE9593 | Down | -0.4483030245 |
| GSE43922 | Down | -3.9438489179 |
| GSE24585 | Up | 0.1332776317 |
| GSE37065 | Up | 0.4933592450 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.6518738629 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
