HCSGD entry for DOCK6
1. General information
| Official gene symbol | DOCK6 |
|---|---|
| Entrez ID | 57572 |
| Gene full name | dedicator of cytokinesis 6 |
| Other gene symbols | AOS2 ZIR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0736548991 | 0.9579347403 | 0.5767238251 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0452605813 |
| GSE13712_SHEAR | Down | -0.1337478001 |
| GSE13712_STATIC | Down | -0.2066555206 |
| GSE19018 | Up | 0.0227977585 |
| GSE19899_A1 | Up | 0.3988399052 |
| GSE19899_A2 | Up | 0.3659065540 |
| PubMed_21979375_A1 | Up | 0.6390858845 |
| PubMed_21979375_A2 | Up | 0.4324949634 |
| GSE35957 | Down | -0.0847014671 |
| GSE36640 | Up | 0.1488181257 |
| GSE54402 | Up | 0.3590606937 |
| GSE9593 | Up | 0.1453023386 |
| GSE43922 | Up | 0.9947622226 |
| GSE24585 | Down | -0.0983293949 |
| GSE37065 | Down | -0.1540325666 |
| GSE28863_A1 | Down | -0.0165232678 |
| GSE28863_A2 | Up | 0.1511331685 |
| GSE28863_A3 | Up | 0.2348885413 |
| GSE28863_A4 | Up | 0.0336992795 |
| GSE48662 | Up | 0.1332730565 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018644 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044102 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord

