HCSGD entry for ALPK3


1. General information

Official gene symbolALPK3
Entrez ID57538
Gene full namealpha-kinase 3
Other gene symbolsMAK MIDORI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusISScellular_component
GO:0007507Heart developmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06345747120.91793927660.54315731471.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0156796470
GSE13712_SHEARUp0.9903319267
GSE13712_STATICUp1.0025587438
GSE19018Up0.1841559730
GSE19899_A1Down-0.0437551745
GSE19899_A2Up0.0014638999
PubMed_21979375_A1Up0.3141594647
PubMed_21979375_A2Down-0.1401586424
GSE35957Down-0.0299727883
GSE36640Down-0.2725746208
GSE54402Up0.9515991839
GSE9593Up0.0079025455
GSE43922Up0.0453685692
GSE24585Down-0.2362927765
GSE37065Up0.1522266974
GSE28863_A1Down-0.0019968747
GSE28863_A2Up0.0764704212
GSE28863_A3Up0.3297882215
GSE28863_A4Up0.1785932408
GSE48662Up0.1316061412

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030251MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.