HCSGD entry for CGN


1. General information

Official gene symbolCGN
Entrez ID57530
Gene full namecingulin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003774Motor activityIEAmolecular_function
GO:0003779Actin bindingISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005923Tight junctionIDA NAScellular_component
GO:0007179Transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0008150Biological_processNDbiological_process
GO:0016459Myosin complexIEAcellular_component
GO:0030054Cell junctionTAScellular_component
GO:0043296Apical junction complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67596748980.87846343220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0868780443
GSE13712_SHEARDown-0.0533102141
GSE13712_STATICDown-0.2928954919
GSE19018Down-0.0404489404
GSE19899_A1Up0.1484642372
GSE19899_A2Up0.0077412675
PubMed_21979375_A1Up0.0731589635
PubMed_21979375_A2Up0.1018885085
GSE35957Up0.0860687260
GSE36640Down-0.1287545995
GSE54402Down-0.0180394812
GSE9593Up0.0519082929
GSE43922Up0.0965468231
GSE24585Up0.2195422101
GSE37065Down-0.0464558214
GSE28863_A1Down-0.0744325993
GSE28863_A2Up0.0752134701
GSE28863_A3Up0.1280800459
GSE28863_A4Up0.0717461331
GSE48662Down-0.0308762308

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-125b-5pMIMAT0000423MIRT004994MicroarrayFunctional MTI (Weak)17891175
hsa-miR-186-5pMIMAT0000456MIRT021173SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031289SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.