HCSGD entry for SERINC1
1. General information
| Official gene symbol | SERINC1 |
|---|---|
| Entrez ID | 57515 |
| Gene full name | serine incorporator 1 |
| Other gene symbols | TDE1L TDE2 TMS-2 TMS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003333 | Amino acid transmembrane transport | ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | ISS | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006658 | Phosphatidylserine metabolic process | ISS | biological_process |
| GO:0006665 | Sphingolipid metabolic process | ISS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0015194 | L-serine transmembrane transporter activity | ISS | molecular_function |
| GO:0015825 | L-serine transport | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | ISS | biological_process |
| GO:0051347 | Positive regulation of transferase activity | ISS | biological_process |
| GO:0055085 | Transmembrane transport | ISS | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0418551309 | 0.8951717906 | 0.4574625311 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2407227027 |
| GSE13712_SHEAR | Up | 0.2738587887 |
| GSE13712_STATIC | Up | 0.2897928106 |
| GSE19018 | Up | 0.4355529211 |
| GSE19899_A1 | Up | 0.0806914980 |
| GSE19899_A2 | Up | 0.0563800905 |
| PubMed_21979375_A1 | Down | -0.8290447239 |
| PubMed_21979375_A2 | Up | 0.0615596773 |
| GSE35957 | Up | 0.5928825276 |
| GSE36640 | Up | 0.8751584060 |
| GSE54402 | Down | -0.1986917240 |
| GSE9593 | Up | 0.7384057829 |
| GSE43922 | Down | -0.1787416148 |
| GSE24585 | Up | 0.5323127233 |
| GSE37065 | Up | 0.1971006504 |
| GSE28863_A1 | Down | -0.1314251454 |
| GSE28863_A2 | Up | 0.3355874895 |
| GSE28863_A3 | Down | -0.2214429388 |
| GSE28863_A4 | Down | -0.2519943061 |
| GSE48662 | Up | 0.4375520326 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-149-5p | MIMAT0000450 | MIRT045614 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049295 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
