HCSGD entry for ISY1


1. General information

Official gene symbolISY1
Entrez ID57461
Gene full nameISY1 splicing factor homolog (S. cerevisiae)
Other gene symbolsFSAP33
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeICbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0071013Catalytic step 2 spliceosomeIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97770050910.10515540060.99999024730.6214048463

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0814698369
GSE13712_SHEARDown-0.1124328627
GSE13712_STATICDown-0.0045622888
GSE19018Down-0.1358464699
GSE19899_A1Down-0.2329747371
GSE19899_A2Down-0.0148753430
PubMed_21979375_A1Down-0.0335400849
PubMed_21979375_A2Down-0.5772735669
GSE35957Down-0.1029635905
GSE36640Down-0.3589907523
GSE54402Up0.0415594829
GSE9593Down-0.1766550708
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.2781694545
GSE28863_A2Down-0.1360061953
GSE28863_A3Up0.0497080293
GSE28863_A4Down-0.3246750440
GSE48662Down-0.0094559589

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039403CLASHFunctional MTI (Weak)23622248
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.