HCSGD entry for SPC25
1. General information
| Official gene symbol | SPC25 |
|---|---|
| Entrez ID | 57405 |
| Gene full name | SPC25, NDC80 kinetochore complex component |
| Other gene symbols | SPBC25 hSpc25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000777 | Condensed chromosome kinetochore | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007052 | Mitotic spindle organization | IMP | biological_process |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0031262 | Ndc80 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9925552677 | 0.0000064625 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.5839950496 |
| GSE13712_SHEAR | Down | -0.2198570985 |
| GSE13712_STATIC | Down | -0.6323250363 |
| GSE19018 | Down | -0.0152399250 |
| GSE19899_A1 | Down | -1.0677706080 |
| GSE19899_A2 | Down | -5.7364558597 |
| PubMed_21979375_A1 | Down | -5.3980916185 |
| PubMed_21979375_A2 | Down | -6.6312624840 |
| GSE35957 | Down | -4.3874426413 |
| GSE36640 | Down | -6.2993839491 |
| GSE54402 | Down | -1.1726423155 |
| GSE9593 | Down | -2.1312557052 |
| GSE43922 | Down | -3.0130964062 |
| GSE24585 | Down | -0.2316367418 |
| GSE37065 | Down | -0.3346516299 |
| GSE28863_A1 | Up | 0.0152383645 |
| GSE28863_A2 | Up | 0.3781764633 |
| GSE28863_A3 | Down | -0.0870592432 |
| GSE28863_A4 | Down | -0.1258811121 |
| GSE48662 | Down | -2.7556723263 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016558 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030123 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
